A woman showing the results of Skin Rejuventation using Polynucleotides at the Skin Emporium clinic in Clapham, London.


Polynucleotides are game changing biostimulators that increase collagen and elastin naturally.

Single session |

£ 350

Course of 2 sessions |

£ 600

Course of 3 sessions |

£ 750

or call us on   0208 6171 121


30 mins in clinic

back to work



little to none


numbing cream


Seen after 2 weeks-3 months

Best results

Seen in 2 weeks-3 months and ongoing

Polynucleotides are chains of nucleotides, the building blocks of DNA and RNA, boasting a structure similar to that of human DNA. When introduced into the body, they act as biostimulators promoting cellular repair, boosting collagen production, and enhancing tissue regeneration.

Polynucleotides often referred to as PN or PDRN ( Polydeoxyribonucleotide), are naturally occurring molecules found within our cells. These remarkable substances play a pivotal role in cellular repair and regeneration, making them a valuable addition to your aesthetic and wellness treatments.

What are the benefits of polynucleotides?

    • Skin Rejuvenation- polynucleotides stimulate collagen and elastin production, leading to smoother, firmer and more youthful looking skin.
    • Reduction of fine lines and wrinkles
    • Reduction in crepiness
    • Fights inflammation which can reduce the effects of Rosacea</li
    • An excellent treatment for patients that are unsuitable for tear tough filler to firm and brighten the under eyes improving the appearance of dark circles or eye bags
    • An excellent preventative treatment for younger skin or a rejuvenating treatment for ageing skin.
    • Sun damage, sun spots or dark patches

Frequently asked questions

Are polynucleotides safe?

Yes, there are no recorded adverse reactions or allergies to polynucleotides

How many treatments will I need?

Two to three treatments are recommended spaced two to four weeks apart

Are they the same as Profhilo or skin boosters?

No, Profhilo and skin boosters are made of hyaluronic acid which means they provide hydration to make skin plumper and fresher without creating structure or changing facial proportions. Polynucleotides will not provide any instant hydration but will provide food for the cells to produce collagen and elastin.

Do they replace traditional dermal fillers?

No, as they cannot create structure or replace lost volume. They do an entirely different job to dermal fillers, and are often used in combination with them.

Is there any downtime?

There is minimal to no downtime, but as with any injectable treatment be prepared for potential swelling or bruising and plan around any social events.

How long does the treatment take?

Around 30 mins including numbing, making it convenient to fit into a busy schedule.


or call us on   0208 6171 121

Philippa S.

I had a filler treatment to my under eyes. As a busy mum I never get a full night’s sleep and my face was looking drawn and tired. I tried so many eye creams and eye masks that didn’t really help at all. I was nervous about getting fillers, but no one would ever know, I just look like I’ve actually had some sleep at last!!

Beth M.

The Skin Emporium clinic was recommended to me by a colleague. I have had several different treatments and have seen real changes, I will definitely keep coming back for more.

Maria B.

I travel across London to see these wonderful ladies, I wouldn’t dream of going anywhere else! They are so kind and caring as well as being the best at what they do.

Natalie H.

I highly recommend Skin Emporium, for the way that they have looked after me and everything they have done for me. I have always struggled with problem skin, since having regular medical facials and using the products they recommended for me the difference has been very noticeable and looking back at photos before you wouldn’t believe it.

Lyander J.

Excellent service. From booking my initial consultation through to having my treatment I was made to feel welcome unlike some clinics I have been to before that treat you like an inconvenience. My skin looks great, tighter and like I did probably 5 years ago. It has really worked and given me amazing confidence.

Francisco A.

Always very friendly service and lovely clinic. I feel very comfortable throughout my appointments and aftercare advice advice has always been great. So nice to find a medical clinic that is not stuffy.

George C.

Quality treatments with a very professional service throughout. I am very happy with everything I have had done here at the clinic and would definitely recommend to anyone looking into these sorts of treatments. The medical staff all have years of experience, which was really important to me after a previous bad experience.


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